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Nutrakare

Antibiotics

Kefodime 50/100 Dt
Composition
Each Dispersible tablet contains:
 

Cefpodoxime Proxetil
50/100 mg
Presentation
Kefodime 50/100/200 is available as a strip of 10 tablets.
Kefodime 200
Composition
Each film coated tablet contains:
 

Cefpodoxime Proxetil
200 mg
Presentation
Kefodime 50/100/200 is available as a strip of 10 tablets.
Kefodime Dry Syrup
Description
Cefpodoxime is an extended spectrum semi-synthetic antibiotic which belongs to the third generation of cephalosporins. It inhibits bacterial cell wall synthesis leading to bacterial cell death.

Cefpodoxime is given as Cefpodoxime proxetil (prodrug) which is hydrolyzed in the intestinal epithelium to release active drug Cefpodoxime. It is active against broad spectrum of Gram +ve & Gram -ve bacteria. Organisms resistant to penicillins and some cephalosporins due to their beta-lactamases secretion are susceptible to Cefpodoxime.

It is effective for longer duration with higher clinical success rate and low incidence of side effects.
Indications
Lower respiratory tract infections
Upper respiratory tract infections
Urinary tract infections including gonorrhea, cystitis
Skin and soft tissue infections
Gynecological infections
Acute otitis media
Composition
Each 5 ml of reconstituted syrup contains:
 

Cefpodoxime Proxetil
50 mg
Dosage
Adults
200mg BID or 400mg OD for 7 -10 days.
In case of URTI & Uncomplicated UTI, dose can be reduced to 100mg BID or 200mg OD.
Only single dose of 200mg is recommended in case of Uncomplicated Gonorrhea.
Children
10 mg/kg/ days or 5 mg/kg every 12 hrs for 10 day (max 400 mg/ day).
Precautions
Pregnancy
Not enough studies to document use in pregnancy.

Nursing Mothers
Cefpodoxime is secreted in human milk. Use with caution.

Pediatric Use
Safety and effectiveness not established in infants (less than two months old).

Adverse reactions
Diarrhea, Nausea, Vomiting, Abdominal pain, & pruritus.
Contraindications
Known hypersensitivity to cefpodoxime proxetil.
Presentation
Kefodime 50/100/200 is available as a strip of 10 tablets.
Kefodime dry syrup is available as a bottle of 30 ml.
Ofoxin 200/400
Composition
Each tablet contains:
 

Ofloxacin
200/400 mg
Presentation
Ofoxin 200/400 is available as a strip of 10 tablets.
Ofoxin Suspension
Description
Ofloxacin is a second generation quinolone antibiotic. Ofloxacin inhibits the bacterial DNA gyrase enzymes required for DNA synthesis (replication, transcription, repair and recombination) and hence exerts rapid bactericidal action.

It exhibits complete (100%) oral bioavailability amongst the fluoroquinolone class.

It is highly effective against typhoid fever resulting from even multi-drug resistant strains and shows greater efficacy than Ciprofloxacin in treatment of enteric fever.

It has also shown excellent activity against pathogens causing urinary tract infection. It is safe, effective and well tolerated.
Indications
Typhoid Fever
GI infection
Urinary Tract Infections
LRTI (Lower Respiratory Tract Infections)
Composition
ofloxacin
50 mg

Dosage
Adults
Usually 200 mg BID is used.
In severe cases 400 mg BID should be used.
Duration of therapy depends on type & severity of infection (3 – 7 days).
Children
1 teaspoonful BID
Adverse reactions
Few side effects like nausea, vomiting, abdominal pain and diarrhoea are seen.

Contraindications

Hypersensitivity to quinolones antibiotics.
Epilepsy.
Presentation
Ofoxin suspension is available in Delicious Mango Flavour presented in a bottle of 30 ml.