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Vazokare
Vazokare Division is catering into Life Style Segments - Cardiology and Diabetology.

The division manufactures and markets the quality brands with the ultimate goal of delivering maximum possible benefits to all its customers.

It also strives at its best in offering the premium quality medicines at the most economical price, thus serving the society.

Vazokare proves its belief in innovation by launching the India’s first and only Glyceryl Trinitrate Spray in pen form.

Our mission is to give access to the best healthcare products at the most affordable price.

Anti hypertensive

PRIMODIL 2.5MG
Description
Primodil (Amlodipine) is the second generation, long-acting calcium channel blocker. It is more selective for vascular smooth muscle than for myocardial tissue. It acts by primarily inhibiting the entry of calcium ions into the vascular smooth muscle. As we know, contractile process of smooth muscle is dependent upon the entry of extra cellular calcium ions into these cells through Ca++ channels. It is more selective for arteries. Thus, Amlodipine is also termed as arterial vasodilator. Because of this mode of action Primodil is effective in the management of mild to moderate hypertension as well as in both stable angina and vasospastic angina angina.
Indications
Hypertension
Composition
Each tab contains:
 

Amlodipine
2.5 mg

Dosage
For hypertension and angina, Primodil is given in the dose of 5 mg once daily. After two weeks, dosage may be increased to a maximum of 10 mg once daily.
Angina pectoris: The dosage may be gradually increased at weekly intervals until optimum clinical response has been obtained.
For elderly patients and patients with hepatic dysfunction, therapy should begin with 2.5 mg once daily.
Side Effects
Amlodipine is well tolerated. Rarely can it cause ankle edema, headache, dizziness, somnolence, etc.
Presentation
PRIMODIL 2.5 MG is available as a strip of 10 tablets
PRIMODIL 5 MG
Description
Primodil (Amlodipine) is the second generation, long-acting calcium channel blocker. It is more selective for vascular smooth muscle than for myocardial tissue. It acts by primarily inhibiting the entry of calcium ions into the vascular smooth muscle. As we know, contractile process of smooth muscle is dependent upon the entry of extra cellular calcium ions into these cells through Ca++ channels. It is more selective for arteries. Thus, Amlodipine is also termed as arterial vasodilator. Because of this mode of action Primodil is effective in the management of mild to moderate hypertension as well as in both stable angina and vasospastic angina angina.
Indications
Hypertension
Composition
Each tab contains:
 

Amlodipine
5 mg

Dosage
For hypertension and angina, Primodil is given in the dose of 5 mg once daily. After two weeks, dosage may be increased to a maximum of 10 mg once daily.
Angina pectoris: The dosage may be gradually increased at weekly intervals until optimum clinical response has been obtained.
For elderly patients and patients with hepatic dysfunction, therapy should begin with 2.5 mg once daily.
Side Effects
Amlodipine is well tolerated. Rarely can it cause ankle edema, headache, dizziness, somnolence, etc.
Presentation
PRIMODIL 5 MG is available as a strip of 10 tablets
PRIMODIL 10 MG
Description
Primodil (Amlodipine) is the second generation, long-acting calcium channel blocker. It is more selective for vascular smooth muscle than for myocardial tissue. It acts by primarily inhibiting the entry of calcium ions into the vascular smooth muscle. As we know, contractile process of smooth muscle is dependent upon the entry of extra cellular calcium ions into these cells through Ca++ channels. It is more selective for arteries. Thus, Amlodipine is also termed as arterial vasodilator. Because of this mode of action Primodil is effective in the management of mild to moderate hypertension as well as in both stable angina and vasospastic angina angina.
Indications
Hypertension
Composition
Each tab contains:
 

Amlodipine
10 mg

Dosage
For hypertension and angina, Primodil is given in the dose of 5 mg once daily. After two weeks, dosage may be increased to a maximum of 10 mg once daily.
Angina pectoris: The dosage may be gradually increased at weekly intervals until optimum clinical response has been obtained.
For elderly patients and patients with hepatic dysfunction, therapy should begin with 2.5 mg once daily.
Side Effects
Amlodipine is well tolerated. Rarely can it cause ankle edema, headache, dizziness, somnolence, etc.
Presentation
PRIMODIL 10 MG is available as a strip of 10 tablets
PRIMODIL - L
Description
Primodil-L is a fixed dose combination of losartan (an angiotensin-II blocker) and amlodipine (a long acting calcium channel blocker) for the management of mild to moderate hypertension where the B.P is not adequately controlled by individual agents alone. Agents acting on renin angiotensin system and calcium channel blockers have an established role in the management of hypertension. Drugs of these two classes reduce B.P by complimentary mechanisms and offer distinct therapeutic advantages. These two potent antihypertensives coupled with less likelihood side effects would be able to achieve the desired goal of maintaining greater reduction in B.P.
Indications
Hypertension with nephropathy
Composition
Each tab contains:
 

Amlodipine
5 mg

Losartan
50 mg

Dosage
Once daily.
Side Effects
The adverse effects seen with the combination were mild in nature. The common side effects are oedema of feet, chest pain, body ache, giddiness and constipation which were mild in nature.
Presentation
PRIMODIL-L is available as a strip of 10 tablets
Encardil 2.5
Description
Encardil contains Enalapril. Enalapril is an antihypertensive agent. It belongs to the second generation of Angiotensin Converting Enzyme (ACE) inhibitors. Enalapril is a prodrug. It gets hydrolysed in the liver to its active form Enalaprilat, which inhibits the Angiotensin Converting Enzyme.
Indications
Hypertension
Congestive heart failure
Post MI
Composition
Each uncoated tablet contains:
Enalapril Maleate - 2.5 mg
Dose
Hypertension: Therapy can be initiated with 2.5 - 5 mg O.D. Maintenance dose is 5 to 20 mg O.D. In elderly patients with impaired renal function, it can be started with 2.5 mg O.D.

Congestive heart failure: Start with 2.5 mg O.D. and can be increased to 10 to 20 mg daily. Post MI: Dose has to be titrated as per the requirement.
Side effects
Encardil is well tolerated. Some of the mild side effects include cough, hyperkalemia and skin rash.
Presentation
Encardil is available as a strip of 10 tablets.
Encardil 5
Description
Encardil contains Enalapril. Enalapril is an antihypertensive agent. It belongs to the second generation of Angiotensin Converting Enzyme (ACE) inhibitors. Enalapril is a prodrug. It gets hydrolysed in the liver to its active form Enalaprilat, which inhibits the Angiotensin Converting Enzyme.
Indications
Hypertension
Congestive heart failure
Post MI
Composition
Each uncoated tablet contains:
Enalapril Maleate - 5 mg
Dose
Hypertension: Therapy can be initiated with 2.5 - 5 mg O.D. Maintenance dose is 5 to 20 mg O.D. In elderly patients with impaired renal function, it can be started with 2.5 mg O.D.

Congestive heart failure: Start with 2.5 mg O.D. and can be increased to 10 to 20 mg daily. Post MI: Dose has to be titrated as per the requirement.
Side effects
Encardil is well tolerated. Some of the mild side effects include cough, hyperkalemia and skin rash.
Presentation
Encardil is available as a strip of 10 tablets.
Encardil 10
Description
Encardil contains Enalapril. Enalapril is an antihypertensive agent. It belongs to the second generation of Angiotensin Converting Enzyme (ACE) inhibitors. Enalapril is a prodrug. It gets hydrolysed in the liver to its active form Enalaprilat, which inhibits the Angiotensin Converting Enzyme.
Indications
Hypertension
Congestive heart failure
Post MI
Composition
Each uncoated tablet contains:
Enalapril Maleate - 10 mg
Dose
Hypertension: Therapy can be initiated with 2.5 - 5 mg O.D. Maintenance dose is 5 to 20 mg O.D. In elderly patients with impaired renal function, it can be started with 2.5 mg O.D.

Congestive heart failure: Start with 2.5 mg O.D. and can be increased to 10 to 20 mg daily. Post MI: Dose has to be titrated as per the requirement.
Side effects
Encardil is well tolerated. Some of the mild side effects include cough, hyperkalemia and skin rash.
Presentation
Encardil is available as a strip of 10 tablets.
Nevol 2.5
Description
Nebivolol is a selective B1-receptor antagonist. Blocking the beta-receptors in the heart causes the heart to beat more slowly and with less force. This means that the pressure at which blood is pumped out of the heart to the rest of the body is reduced.

It has mild vasodilating properties, possible due to an interaction with the L-arginine/nitric oxide pathway, which widens the blood vessels.

Nebivolol with its distinct mechanism of action is very good antihypertensive and useful for the treatment of mild to moderate hypertension.
Indications
Treatment of mild to moderate essential hypertension
Composition
Each tablet contains:
Nebivolol Hydrochloride   2.5 mg
Dosage
5 mg tablet once daily, preferable at the same time of the day, with or without meals.
Patients with renal insufficiency the recommended starting dose is 2.5 mg daily.
The daily dose may be increased to 5 mg if needed.
Elderly patients over 65 years, the recommended starting dose is 2.5 mg daily. The dose may be increased to 5 mg daily if needed.
Side Effects
Headache, bradycardia, diarrhea, constipation, nausea, vomiting or abdominal pain.
Contraindications
Hypersensitivity to Nebivolol
Liver function impairment
Cardiogenic shock
Not recommended for use in pregnancy, lactation and children
Precaution
Use cautiously in patients with history of bronchial asthma.
Presentation
Nevol is available as a strip of 10 tablets.
Nevol 5
Description
Nebivolol is a selective B1-receptor antagonist. Blocking the beta-receptors in the heart causes the heart to beat more slowly and with less force. This means that the pressure at which blood is pumped out of the heart to the rest of the body is reduced.

It has mild vasodilating properties, possible due to an interaction with the L-arginine/nitric oxide pathway, which widens the blood vessels.

Nebivolol with its distinct mechanism of action is very good antihypertensive and useful for the treatment of mild to moderate hypertension.
Indications
Treatment of mild to moderate essential hypertension
Composition
Each tablet contains:
Nebivolol Hydrochloride   5mg
Dosage
5 mg tablet once daily, preferable at the same time of the day, with or without meals.
Patients with renal insufficiency the recommended starting dose is 2.5 mg daily.
The daily dose may be increased to 5 mg if needed.
Elderly patients over 65 years, the recommended starting dose is 2.5 mg daily. The dose may be increased to 5 mg daily if needed.
Side Effects
Headache, bradycardia, diarrhea, constipation, nausea, vomiting or abdominal pain.
Contraindications
Hypersensitivity to Nebivolol
Liver function impairment
Cardiogenic shock
Not recommended for use in pregnancy, lactation and children
Precaution
Use cautiously in patients with history of bronchial asthma.
Presentation
Nevol is available as a strip of 10 tablets.
Nevol H
Description
Hypertension is a multifactorial disease. One drug addresses only one physiological pathway of many that leads to hypertension.

The other mechanisms of blood pressure regulation will be stimulated and play major role in raising the B.P. Hence two or more agents from different pharmacological classes are often needed to achieve adequate blood pressure control.

Nebivolol has dual mode of action: It is a competitive & selective β1-receptor antagonist & it has mild vasodilating properties.

Nebivolol reduces heart rate & blood pressure at rest & during exercise. Acute effects of thiazides are as a result of a reduction in blood volume and cardiac output, secondary to a natriuretic effect. Better blood pressure control can be achieved by using this combination.
Indications
Management of hypertension not responding to monotherapy.
Hypertension with left ventricular failure.
Composition
Each tablet contains:
Nebivolol Hydrochloride - 5 mg
Hydrochlorothiazide - 12.5 mg
Dosage
One tablet daily preferably at the same time of the day.
Side Effects
Anaphylactic reaction, Headache, Dizziness, Paresthesia, Constipation, Nausea, Dyspnoea.
Contraindications
Cardiogenic shock, overt cardiac failure, Heart block, bradycardia, anuria, and hypersensitivity to either component of this product or to other sulfonamide-derived drugs
Presentation
Nevol-H is available as a strip of 10 tablets.
Telmed 20 MG
Description
Telmisartan, a unique angiotensin II receptor antagonist used for the treatment of hypertension, also function as a partial agonist of PPAR gamma receptor; and reduce glucose, insulin, and triglyceride levels. None of the other available angiotensin II receptor antagonists activate PPAR when tested at concentrations typically achieved in plasma with conventional oral dosing. In contrast to ordinary antihypertensive and antidiabetic agents, molecules that can simultaneously block the angiotensin II receptor and activate PPAR have the potential to treat both hypertension and biochemical features of the metabolic syndrome and could provide unique opportunities for the prevention and treatment of diabetes and cardiovascular disease in high-risk populations.
Indications
TELMED is indicated for the treatment hypertension with nephropathy.
Composition
Each tablet contains:
 

Telmisartan
20 mg

Dosage
Usual starting dose of TELMED is 20 mg once a day;
Side Effects
Fatigue, sinusitis, respiratory tract infection.
Presentation
Telmed 20 MG is available as a strip of 10 tablets
Telmed 40 MG
Description
Telmisartan, a unique angiotensin II receptor antagonist used for the treatment of hypertension, also function as a partial agonist of PPAR gamma receptor; and reduce glucose, insulin, and triglyceride levels. None of the other available angiotensin II receptor antagonists activate PPAR when tested at concentrations typically achieved in plasma with conventional oral dosing. In contrast to ordinary antihypertensive and antidiabetic agents, molecules that can simultaneously block the angiotensin II receptor and activate PPAR have the potential to treat both hypertension and biochemical features of the metabolic syndrome and could provide unique opportunities for the prevention and treatment of diabetes and cardiovascular disease in high-risk populations.
Indications
TELMED is indicated for the treatment hypertension with nephropathy.
Composition
Each tablet contains:
 

Telmisartan
40 mg

Dosage
Usual starting dose of TELMED is 40 mg once a day;
Side Effects
Fatigue, sinusitis, respiratory tract infection.
Presentation
Telmed 40 MG is available as a strip of 10 tablets
Telmed 80 MG
Description
Telmisartan, a unique angiotensin II receptor antagonist used for the treatment of hypertension, also function as a partial agonist of PPAR gamma receptor; and reduce glucose, insulin, and triglyceride levels. None of the other available angiotensin II receptor antagonists activate PPAR when tested at concentrations typically achieved in plasma with conventional oral dosing. In contrast to ordinary antihypertensive and antidiabetic agents, molecules that can simultaneously block the angiotensin II receptor and activate PPAR have the potential to treat both hypertension and biochemical features of the metabolic syndrome and could provide unique opportunities for the prevention and treatment of diabetes and cardiovascular disease in high-risk populations.
Indications
TELMED is indicated for the treatment hypertension with nephropathy.
Composition
Each tablet contains:
 

Telmisartan
80 mg

Dosage
One tablet once daily
Side Effects
Fatigue, sinusitis, respiratory tract infection.
Presentation
Telmed 80 MG is available as a strip of 10 tablets
TELMED – AH 40
Description
Hypertension being a multifactorial disease, management of hypertension often requires multiple drugs. 23%–52% patients require three or more antihypertensive agents for BP control and to achieve JNC VII target. Combining drugs with complimentary modes of action is practically correct, as it is more likely to achieve better BP control. Combining drugs reduces the adverse events of the high dose monotherapies. A triple drug combination therapy would be a desirable treatment option for hypertension uncontrolled on dual drug. Combining different drugs in a single pill leads to better compliance and hence better BP control.
Indications
Hypertension uncontrolled on dual therapy
Stage 2 hypertension
Composition
Telmed - AH 40
 

Each tablet contains:
 

Telmisartan
40 mg

Amlodipine
5 mg

Hydrochlorothiazide
12.5mg

Dosage
1 tablet to be taken once daily preferably at the same time everyday
Presentation
Telmed - AH 40 is available as a strip of 10 tablets
TELMED – AH 80
Description
Hypertension being a multifactorial disease, management of hypertension often requires multiple drugs. 23%–52% patients require three or more antihypertensive agents for BP control and to achieve JNC VII target. Combining drugs with complimentary modes of action is practically correct, as it is more likely to achieve better BP control. Combining drugs reduces the adverse events of the high dose monotherapies. A triple drug combination therapy would be a desirable treatment option for hypertension uncontrolled on dual drug. Combining different drugs in a single pill leads to better compliance and hence better BP control.
Indications
Hypertension uncontrolled on dual therapy
Stage 2 hypertension
Composition
Telmed - AH 80
 

Each tablet contains:
 

Telmisartan
80 mg

Amlodipine
5 mg

Hydrochlorothiazide
12.5mg

Dosage
1 tablet to be taken once daily preferably at the same time everyday
Presentation
Telmed - AH 80 is available as a strip of 10 tablets
TELMED –AM
Description
The goal set by JNC VII in diabetic hypertensive is 130/80 mm Hg that is very difficult to achieve with monotherapy. However, older antihypertensive agents such as thiazide diuretics and beta-blockers have potentially adverse effects on glucose and lipid metabolism and may even exacerbate the metabolic syndrome and increase risk of type II diabetes. Thus, there is a need for an antihypertensive drug combination that can achieve the JNC VII recommended goal without compromising the lipid profile and glycaemic control. Telmisartan plus Amlodipine are two potent antihypertensives with less side effects that would be able to achieve the desired goal of maintaining greater reduction in B.P.
Indications
Diabetic hypertensives
Hypertension not controlled with monotherapy
Composition
Each tablet contains:
 

Telmisartan
40 mg

Amlodipine
5 mg

Dosage
One tablet once daily
Side Effects
URTI, Dizziness, Diarrhea, ankle edema, Headache
Presentation
Telmed-AM is available as a strip of 10 tablets.
TELMED –H 40
Description
Diuretics are effective antihypertensive drugs. In long-term trials, diuretics have been shown to reduce the incidence of stroke, congestive heart failure, coronary artery disease and total mortality from cardiovascular disease. Telmisartan exerts antihypertensive effect by selectively blocking the angiotensin II type 1 (AT1) receptors. Hypokalemia caused by diuretics, counteract the positive cardiovascular benefits of blood pressure reduction. Telmisartan protects against potassium depletion, a common side effect of thiazide monotherapy. Thus low dose hydrochlorothiazide in combination with Telmisartan does not counteract the positive cardiovascular benefits of blood pressure reduction and helps in achieving the desired goal of BP.
Indications
Hypertension uncontrolled with monotherapy
Composition
Each tablet contains :
 

Telmisartan
40 mg

Hydrochlorothiazide
12.5 mg

Dosage
One tablet daily
Side Effects
Most adverse experiences are mild in intensity and transient in nature like Fatigue, dizziness, nausea, sinusitis, respiratory tract infections.
Presentation
TELMED –H 40 is available as a strip of 10 tablets
TELMED –H 80
Description
Diuretics are effective antihypertensive drugs. In long-term trials, diuretics have been shown to reduce the incidence of stroke, congestive heart failure, coronary artery disease and total mortality from cardiovascular disease. Telmisartan exerts antihypertensive effect by selectively blocking the angiotensin II type 1 (AT1) receptors. Hypokalemia caused by diuretics, counteract the positive cardiovascular benefits of blood pressure reduction. Telmisartan protects against potassium depletion, a common side effect of thiazide monotherapy. Thus low dose hydrochlorothiazide in combination with Telmisartan does not counteract the positive cardiovascular benefits of blood pressure reduction and helps in achieving the desired goal of BP.
Indications
Hypertension uncontrolled with monotherapy
Composition
Each tablet contains :
 

Telmisartan
80 mg


Hydrochlorothiazide
12.5 mg

Dosage
One tablet daily
Side Effects
Most adverse experiences are mild in intensity and transient in nature like Fatigue, dizziness, nausea, sinusitis, respiratory tract infections.
Presentation
TELMED –H 80 is available as a strip of 10 tablets
TELMED BETA 25
Description
Fixed-dose combination that target complementary BP-lowering mechanisms like Heart rate, Peripheral Resistance and Cardiac Output provides an effective approach for better BP control. Telmisartan exerts antihypertensive effect by selectively blocking AT1 receptors; resulting into blocking the actions of angiotensin II, including vasoconstriction, sodium and water retention and sympathetic nervous system activation. Metoprolol is cardio selective β1 blocker. It causes decrease in heart rate and cardiac output and thus decreases blood pressure.
Indications
Hypertension uncontrolled on monotherapy
Hypertension with heart failure
Hypertension with CAD
Composition
Each Tablet of Telmed Beta Consists of:
 

Metoprolol
25 mg

Telmisartan
40 mg

Presentation
TELMED BETA 25 is available as a strip of 10 tablets
TELMED BETA 50
Description
Fixed-dose combination that target complementary BP-lowering mechanisms like Heart rate, Peripheral Resistance and Cardiac Output provides an effective approach for better BP control. Telmisartan exerts antihypertensive effect by selectively blocking AT1 receptors; resulting into blocking the actions of angiotensin II, including vasoconstriction, sodium and water retention and sympathetic nervous system activation. Metoprolol is cardio selective β1 blocker. It causes decrease in heart rate and cardiac output and thus decreases blood pressure.
Indications
Hypertension uncontrolled on monotherapy
Hypertension with heart failure
Hypertension with CAD
Composition
Each Tablet of Telmed Beta Consists of:
 

Metoprolol
50 mg

Telmisartan
40 mg

Presentation
TELMED BETA 50 is available as a strip of 10 tablets
Telmed CT 40 tablet
Composition
Each tablet contains:
Telmisartan 40 mg
Chlorthalidone 12.5 mg
Indications
Hypertension & CV risk
Presentation
TELMED CT 40 is available as a strip of 10 tablets
Telmed CT 80 tablet
Composition
Each tablet contains:
Telmisartan 80 mg
Chlorthalidone 12.5 mg
Indications
Hypertension & CV risk
Presentation
TELMED CT 80 is available as a strip of 10 tablets
Telmed ACT 40 tablet
Composition
Each tablet contains:
Telmisartan 40 mg
Amlodipine 5 mg
Chlorthalidone 12.5 mg
Indications
Hypertension uncontrolled on dual therapy
Stage II hypertension with nephropathy
Hypertension with CKD
Presentation
Telmed-ACT 40 is available as a strip of 10 tablets
Telmed ACT 80 tablet
Composition
Each tablet contains:
Telmisartan 80 mg
Amlodipine 5 mg
Chlorthalidone 12.5 mg
Indications
Hypertension uncontrolled on dual therapy
Stage II hypertension with nephropathy
Hypertension with CKD
Presentation
Telmed-ACT 80 is available as a strip of 10 tablets
CILDIP 5
Description
Cilnidipine is a Calcium channel blocker. It block both type of calcium channel. Inhibits L-type calcium channel resulting in vasodilation .Inhibits N-type calcium channel resulting in no sympathetic activation thus reduces heart rate. Both these effects leads to decrease in blood pressure with less chances of ankle/pedal edema. Cilnidipine also Improves insulin sensitivity & Increases Nitric Oxide production thus improves endothelial function.
Indications
In the management of :
Hypertension
Hypertension with diabetes mellitus
Hypertension and chronic renal insufficiency
Hypertension in elderly
Composition
Each tablet contains :
 

Cilnidipine
5 mg

Dosage & Administration
Cilnidipine's starting dose is 5 mg/day orally.
Maximum 20mg/day.
Presentation
Cildip is available as a strip of 10 tablets
CILDIP 10
Description
Cilnidipine is a Calcium channel blocker. It block both type of calcium channel. Inhibits L-type calcium channel resulting in vasodilation .Inhibits N-type calcium channel resulting in no sympathetic activation thus reduces heart rate. Both these effects leads to decrease in blood pressure with less chances of ankle/pedal edema. Cilnidipine also Improves insulin sensitivity & Increases Nitric Oxide production thus improves endothelial function.
Indications
In the management of :
Hypertension
Hypertension with diabetes mellitus
Hypertension and chronic renal insufficiency
Hypertension in elderly
Composition
Each tablet contains :
 

Cilnidipine
10 mg

Dosage & Administration
Cilnidipine's starting dose is 5 mg/day orally.
Maximum 20mg/day.
Presentation
Cildip is available as a strip of 10 tablets
CILDIP 20
Description
Cilnidipine is a Calcium channel blocker. It block both type of calcium channel. Inhibits L-type calcium channel resulting in vasodilation .Inhibits N-type calcium channel resulting in no sympathetic activation thus reduces heart rate. Both these effects leads to decrease in blood pressure with less chances of ankle/pedal edema. Cilnidipine also Improves insulin sensitivity & Increases Nitric Oxide production thus improves endothelial function.
Indications
In the management of :
Hypertension
Hypertension with diabetes mellitus
Hypertension and chronic renal insufficiency
Hypertension in elderly
Composition
Each tablet contains :
 

Cilnidipine
20 mg

Dosage & Administration
Cilnidipine's starting dose is 5 mg/day orally.
Maximum 20mg/day.
Presentation
Cildip is available as a strip of 10 tablets
CILDIP T
Description
Telmisartan amongst ARBs, acts as a partial agonist of PPAR- γ (Peroxisome Proliferator Activated Receptor- Gamma) receptor, helps in improving blood glucose and lipid profile. Cilnidipine improve GLUT-4 receptor, which lead to increase in glucose uptake. Thus, improve insulin sensitivity. Thus, combination of Telmisartan with Cilnidipine improves glucose levels and insulin sensitivity along with decrease in blood pressure. In Renally compromised patients Telmisartan which is mainly excreted through hepatic route can be safely given to hypertensive patients who suffer from nephropathy and there is no need to reduce the dose. N-type Ca2+ channels are present in both afferent and efferent arterioles. Their inhibition by Cilnidipine elicits vasodilation of both arterioles, leading to the reduction in glomerular pressure. This results in decrease in proteinuria. Thus, combination of telmisartan and Cilnidipine is beneficial in the hypertensives with kidney disease.
Indications
Stage II hypertension
Hypertension uncontrolled with monotherapy
Diabetic hypertensive patients
Hypertension with nephropathy
Composition
Each tablet contains :
 

Telmisartan
40 mg

Cilnidipine
10 mg

Dosage
Once daily preferably at the same time of the day
Presentation
Cildip is available as a strip of 10 tablets
Cildip 3D tablet
Composition
Each tablet contains:
Cilnidipine 10 mg
Telmisartan 40 mg
Chlorthalidone 6.25 mg
Indications
Stage II & Refractory Hypertension
Presentation
Cildip 3D is available as a strip of 10 tablets